Lactation Biology
نویسندگان
چکیده
J. Anim. Sci. Vol. 87, E-Suppl. 2/J. Dairy Sci. Vol. 92, E-Suppl. 1 (P ≤ 0.1) P3 activity (1.87 vs. 0.34 arbitrary units for stearic vs. control, respectively). Activity of P2 was not altered (P ≥ 0.05) by any treatments and there was no response to glucocorticoids or unsaturated fatty acids for any of the promoters tested. Stearic acid suppresses the activity of bovine PC promoter 1 but enhances the activity of promoter 3 creating a net increase in promoter activity. These data demonstrate the role of fatty acids in regulating PC expression. The specificity of response for PC promoter function to stearic acid in the current data suggests a physiological role for elevated stearic acid concentrations previously observed in transition cows at calving.
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